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Inosine could be a potential route to the first RNA and the origin of life on Earth Harvard University, December 3, 2018, https://phys.org/news/2018-12-inosine-potential-route-rna-life.html The paper is: Seohyun Chris Kim, Derek K. O’Flaherty, Lijun Zhou, Victor S. Lelyveld, and Jack W. Szostak, 2018, Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA. PNAS published ahead of print December 3, 2018 https://doi.org/10.1073/pnas.1814367115 Yours, Paul H.