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Scientists reveal how first cells could have formed on Earth
Oxytropidoceras posted a topic in Fossil News
Scientists reveal how first cells could have formed on Earth by The Scripps Research Institute, PhysOrg, February 29, 2024 The paywalled paper is: Pulletikurti, S., Veena, K.S., Yadav, M., Deniz, A.A. and Krishnamurthy, R., 2024. Experimentally modeling the emergence of prebiotically plausible phospholipid vesicles. Chem. Yours, Paul H.- 1 reply
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How did life begin? One key ingredient is coming into view A Nobel-prizewinning scientist’s team has taken a big step forward in its quest to reconstruct an early-Earth RNA capable of building proteins. Amber Dance, Nature News, February 28, 2023 Ancient protein study reveals how natural selection predates life itself By Michael Irving, News Atlas, February 28, 2023 Ancient protein study reveals how natural selection predates life itself John Hopkins University, February 28, 2023 One paper is: Makarov, M., Sanchez Rocha, A.C., Krystufek, R., Cherepashuk, I., Dzmitruk, V., Charnavets, T., Faustino, A.M., Lebl, M., Fujishima, K., Fried, S.D. and Hlouchova, K., 2022. Early selection of the amino acid alphabet was adaptively shaped by biophysical constraints of foldability. Jounral of the American Chemical Society. Abstract of paywalled paper PDF of Preprint Yours, Paul H.
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Newly discovered chemical reactions could explain the origin of life
Oxytropidoceras posted a topic in Fossil News
Newly discovered chemical reactions could explain the origin of life By Michael Irving, New Atlas, July 29, 2022 Primordial Soup: Scientists Discover New “Origins of Life” Chemical Reactions Scripps Research Institute, July 29, 2022 The paper is: Krishnamurthy, R., Pulletikurti, S., Yadav, M. and Springsteen, G., 2021. Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways. 28 July 2022, Nature Chemistry. DOI: 10.1038/s41557-022-00999-w Yours, Paul H.-
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Scientists announce a breakthrough in determining life's origin on Earth—and maybe Mars Foundation for Applied Molecular Evolution, June 3, 2022 The open access paper is: Craig A. Jerome, Hyo-Joong Kim, Stephen J. Mojzsis, Steven A. Benner, and Elisa Biondi. Catalytic Synthesis of Polyribonucleic Acid on Prebiotic Rock Glasses Astrobiology. ahead of print http://doi.org/10.1089/ast.2022.0027 Yours, Paul H.
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Lightning may have provided prebiotic phosphorus for the origin of life on Earth
Oxytropidoceras posted a topic in Fossil News
How A Building Block Of Life Got Created In A Flash Heard on Morning Edition, NPR, March 16, 2021 Lightning may have sparked life on Earth By Ashley Strickland, CNN, March 16, 2021 The open access paper is: Hess, B.L., Piazolo, S. and Harvey, J. 2012, Lightning strikes as a major facilitator of prebiotic phosphorus reduction on early Earth. Nature Communications 12, 1535 Yours, Paul H.-
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A New Clue to How Life Originated A long-standing mystery about early cells has a solution— and it’s a rather magical one. Ed Young, The Atlantic https://www.theatlantic.com/science/archive/2019/08/interlocking-puzzle-allowed-life-emerge/595945/ Did Amino Acids Stabilize Prebiotic Membranes? A possible solution to a long-standing question about early cells Astrobiology at NASA https://astrobiology.nasa.gov/news/solving-a-long-standing-origin-of-life-puzzle/ First cells may have emerged because building blocks of proteins stabilized membranes, University of Washington, August 12, 2019 https://www.sciencedaily.com/releases/2019/08/190812155502.htm The paper is: Caitlin E. Cornell, Roy A. Black, Mengjun Xue, Helen E. Litz, Andrew Ramsay, Moshe Gordon, Alexander Mileant, Zachary R. Cohen, James A. Williams, Kelly K. Lee, Gary P. Drobny, and Sarah L. Keller. Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes. PNAS, 2019 DOI: 10.1073/pnas.1900275116 https://www.pnas.org/content/early/2019/08/06/1900275116 Yours, Paul H.
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Inosine could be a potential route to the first RNA and the origin of life on Earth Harvard University, December 3, 2018, https://phys.org/news/2018-12-inosine-potential-route-rna-life.html The paper is: Seohyun Chris Kim, Derek K. O’Flaherty, Lijun Zhou, Victor S. Lelyveld, and Jack W. Szostak, 2018, Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA. PNAS published ahead of print December 3, 2018 https://doi.org/10.1073/pnas.1814367115 Yours, Paul H.
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Scientists identify protein that may have existed when life began The primordial peptide may have appeared 4 billion years ago Rutgers University, August 30, 2018 https://www.sciencedaily.com/releases/2018/08/180830180101.htm “The Primordial Protein” Could have Emerged Spontaneously on Earth–Scientists Close in on How Life Began, Daily Galaxy https://dailygalaxy.com/2018/08/the-primordial-protein-could-have-emerged-spontaneously-on-earth-scientists-close-in-on-how-life-began/ J. Dongun Kim, Douglas H. Pike, Alexei M. Tyryshkin, G. V. T. Swapna, Hagai Raanan, Gaetano T. Montelione, Vikas Nanda, Paul G. Falkowski. Minimal Heterochiral de Novo Designed 4Fe–4S Binding Peptide Capable of Robust Electron Transfer. Journal of the American Chemical Society, 2018; DOI: 10.1021/jacs.8b07553 https://pubs.acs.org/doi/10.1021/jacs.8b07553 https://www.ncbi.nlm.nih.gov/pubmed/30141918 Yours, Paul H.
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Why Extraterrestrial Life May Be More Unlikely Than Scientists Thought
Oxytropidoceras posted a topic in Fossil News
Why Extraterrestrial Life May Be More Unlikely Than Scientists Thought https://www.eurekalert.org/pub_releases/2018-04/ras-pop040318.php https://www.telegraph.co.uk/news/2018/04/05/alien-life-may-unlikely-previously-thought-according-new-study/ https://www.livescience.com/62248-extraterrestrial-life-phosphorus.html Phil Cigan https://www.researchgate.net/scientific-contributions/2058521845_Phil_Cigan An unrelated, but interesting article is: The Scientific Paper Is Obsolete. Here’s what’s next. James Somer, The Atlantic, April 5, 2018 https://www.theatlantic.com/science/archive/2018/04/the-scientific-paper-is-obsolete/556676/ Yours, Paul H.- 1 reply
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